Having got the building design right for your pharmaceutical manufacturing needs, whether that is a single story manufacturing floor or multiple floors, it is important to choose the right container-based materials transfer system that will ensure that your pharmaceutical equipment is functioning well and factory production flow is optimized. As you start to investigate which IBC is the best, don't be driven by price alone. What initially looks like a cheaper option may not give you the performance you ultimately need. It is worth doing your research and understanding the benefits and limitations of the different types of IBC on the market today. We have created a handy checklist of the types of questions to ask when making that selection.
The type of IBC you choose depends on many different factors which we will explore in a series of blogs over the coming weeks. This blog looks at what to consider if you have a product that is prone to segregation as it transfers between equipment for Pharmaceutical Manufacturing.
If the material de-mixes or segregates as it is being fed into the tablet press it will result in the incorrect proportions of active ingredient in each tablet – and result in batches having to be scrapped. If you can’t guarantee production quality it will lead to issues with the regulatory authorities.
To prevent the problem of powder blend segregation you need to look for IBCs that promote mass-flow discharge. Upon discharge, all the material in the container moves at the same rate across the whole container, creating uniform flow – no stagnant material, no rat-holing and a first in-first out sequence of material movement.
At the heart of the Matcon IBC system is our unique Cone Valve that has been used by the Pharmaceutical industry for over 35 years. As the cone lifts, it creates an annular gap at the outlet of the IBC which results in all product in the IBC cross-section moving at the same time. Material prefers to flow down the vessel walls rather than the core, consequently there is no movement of individual particles across each other, or rolling or dead zones – hence no segregation. All material has a uniform residence time within the IBC. It ensures a regular feed of product to the downstream pharmaceutical equipment, which is of a high quality and will meet the regulatory standards.
By using Matcon Cone Valve IBCs you maintain a perfectly homogenous mix right to the end of the batch, imperative to ensuring a top quality product every time and no scrapped batches of product. See the Cone Valve in action.
A further vital aspect to achieving a successful installation of an IBC system lies with the experience of how to apply the technology into the various processing steps and connect it to your existing pharmaceutical equipment. This is where the Matcon team offers great value – we strive to supply you with a system that brings you the maximum profitability and product quality. We aren’t just selling IBCs as a commodity, we take a full look at what your manufacturing needs are and designing a system that handles your batches in the right quantities, optimises the use of processing equipment and reduces the amount of manual handling needed to produce your product. We help you to make the right investment.
In order to help you select the right IBC for your needs, we have compiled a helpful checklist of questions to ask potential suppliers to ensure you make the right pharmaceutical equipment choices.